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ICD-10-CM is the official system of assigning codes to diagnoses and procedures associated with hospital utilization in the United States.

CDC released the FY2025 ICD-10-CM with 252 new codes,36 code deletions,13 code revisions making the cut, going into effect on October 1, 2024.

Key Features:

Index of Drugs and Chemicals

Index of Diseases and Injuries

Index of External Causes of Injuries

Index of Neoplasm

The National Center for Health Statistics (NCHS) and the Centers for Medicare and Medicaid Services are the U.S. governmental agencies responsible for overseeing all changes and modifications to the ICD-10-CM.

Highlights from the new 2025 ICD-10-CM codes

ICD-10 codes for cancer in remission

The neoplasm chapter contains codes for most benign and all malignant neoplasms. Chapter 2-Neoplasms leads the way this year in the quantity of new codes, receiving .63 new codes expanding cancer to include "in remission."

C81.1ANodular sclerosis Hodgkin lymphoma, in remission

C81.2AMixed cellularity Hodgkin lymphoma, in remission

C81.3ALymphocyte depleted Hodgkin lymphoma, in remission

C82.5ADiffuse follicle center lymphoma, in remission

C82.6ACutaneous follicle center lymphoma, in remission

Updates to ICD-10 codes for Hypolycemia & Obesity

Chapter 4 –Endocrine, nutritional & metabolic diseases adds level & class to Hypolycemia and Obesity.

E16.A2Hypoglycemia level 2

E16.A3Hypoglycemia level 3

E66.81Obesity class

E66.811Obesity,class 1

E74.82Disorders of citrate metabolism

E74.820SLC13A5 Citrate Transporter Disorder

E74.829Other disorders of citrate metabolism

ICD-10 codes for mental health disorders

In the 2025 update of ICD-10-CM,Chapter 5–Mental & Behavioral Disorders adds type & severity to eating disorders & 2 new codes for mental & behavioral conditions in adults.

F50.010 Anorexia nervosa, restricting type,mild

F50.023Anorexia nervosa, binge eating/purging type, xtreme

F50.21 Bulimia nervosa,mild

F50.814Binge eating disorder,in remission

F50.83Pica in adults

F50.84 Rumination disorder in adults

Updated ICD-10 codes for diseases of the digestive system

Chapter 11–Diseases of the Digestive System adds 5th & 6th character codes for conditions for 2025, providing additional details on the complexity of the condition.

K60.311Anal fistula, simple, initial

K60.32Anal fistula, complex

K60.413Rectal fistula, simple, recurrent

K60.422Rectal fistula, complex, persistent

K60.50 Anorectal fistula, unspecified

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Publisher:Centers for Disease Control & Prevention